Efficacy and safety of laquinimod in multiple sclerosis: current status
نویسندگان
چکیده
منابع مشابه
Comparing the Safety and Efficacy of Ziferon and Betaferon in Patients With Remitting-Relapsing Multiple Sclerosis
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Multiple sclerosis (MS) is a chronic autoimmune disorder of central nervous system. This demyelinating disease affects more than 2.3 million people world wild. Most of patients are young adult. The most common type of MS is relapsing remitting multiple sclerosis (RRMS). However there is no cure, available modifying therapies has revolutionized the care of patients with RRMS. Interferon (IFN) be...
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BACKGROUND Multiple sclerosis (MS) is a chronic autoimmune disease of the CNS. Early treatment reduces the number of relapses, limits progression of disability, and improves quality of life; however, existing therapies are only partially effective and require parenteral administration. OBJECTIVE To review current experience with laquinimod as a novel immunomodulatory therapy for MS. RESULTS...
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BACKGROUND The results of two randomized phase 3 trials that investigated the use of laquinimod in patients with relapsing-remitting multiple sclerosis were analyzed using a propensity score model. METHODS The propensity score in each study was defined as the probability of an individual patient being assigned to either the laquinimod or placebo study arm. The analysis included two main stage...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Neurological Disorders
سال: 2013
ISSN: 1756-2864,1756-2864
DOI: 10.1177/1756285613499424